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Shockwave therapy, a noninvasive treatment that applies extracorporeal shock waves to the penile shaft, can provide mild to moderate improvement in patients with erectile dysfunction of varying etiologies, including vascular, neurogenic, and procedural causes. It can also benefit patients for whom previous medical therapies were not effective. (Strength of Recommendation: A, meta-analysis of randomized controlled trials [RCTs] and four RCTs.)